Linezolid drug interactions: A retrospective study
نویسندگان
چکیده
منابع مشابه
Linezolid tolerability in multidrug-resistant tuberculosis: a retrospective study.
Linezolid is used off-label to treat multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) [1, 2]. Recently, two systematic reviews and meta-analyses pointed out its promising efficacy [3, 4]. However, linezolid toxicity may outweigh its potential benefits. Indeed, adverse events were notified in almost 60% of the treated cases, with a high incidence of severe events ...
متن کاملPrevalence of drug-drug interactions in the era of HIV integrase inhibitors: a retrospective clinical study.
BACKGROUND Antiretroviral agents pose a high risk for drug-drug interactions (DDIs), mainly but not limited to being a substrate, inducer or inhibitor of P450 cytochrome enzymes. In part metabolised by other pathways, integrase inhibitors might show a more favourable profile. The aim of this study was to investigate the prevalence of DDIs in daily clinical practice for patients starting differe...
متن کامل[Hospital readmissions related to drug interactions: a retrospective study in a hospital setting].
OBJECTIVE To examine the relationship between potential drug interactions and hospital readmissions. METHODS Retrospective study with 1,487 adult patients (> 18 years old) admitted to a general hospital in the city of Vitória da Conquista, Northeastern Brazil, from January to December 2007. Data were collected from Hospital Admission Authorization (AIH) forms in the Brazilian National Health ...
متن کاملStudy of Drug-Drug Interactions in Prescriptions of General Practitioners and Specialists in Iran 2007-2009
Prescriptions written by general practitioners and medical specialists were studied and compared to determine the type, time of onset and clinical importance of drug-drug interactions (DDIs) in an attempt to reduce further complications. In 2007, 28, 956, 638 prescriptions and 15, 610, 912 prescriptions in 2008 were filled by pharmacies affiliated with medical science universities. These prescr...
متن کاملTherapeutic drug monitoring: linezolid too?
Numerous factors interfere with the ability to achieve optimal pharmacokinetic and pharmacodynamic targets and this has been associated with greater mortality and lower cure rates. The recent study by Zoller and colleagues examining linezolid levels in critically ill patients emphasises this point. Their study is unique in the description of the intra-patient and inter-patient variability that ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medicine Science | International Medical Journal
سال: 2020
ISSN: 2147-0634
DOI: 10.5455/medscience.2019.08.9190